@Article{info:doi/10.2196/39764，作者="Gudmundsson, G Haukur和M{\'e}sz{\'a}ros, Judit和Bj{\ 'o} rnsd{\'o}ttir， {\'a} G {\'u}sta e和{\'a} mundad{\'o}ttir, Mar{\'i}a L和Thorvardardottir, Gudrun e和Magnusdottir, Erna和Helgadottir, Halla和Oddsson, Saemundur"，标题="评估癌症患者积极治疗期间数字化治疗方案的可行性:介入前-后研究”，期刊=“JMIR Form Res”，年=“2022”，月=“Oct”，日=“13”，卷=“6”，号=“10”，页=“e39764”，关键词=“癌症;生活方式;生活质量;手机应用程序;数字疗法;自我管理;身体活动;背景:越来越多的证据表明，生活方式干预可以改善癌症患者的症状、生活质量(QoL)，甚至整体生存。数字疗法(DTx)可以帮助实施行为改变，并通过教育、生活方式支持和远程症状监测来增强患者的能力。 Objective: We aimed to test the feasibility of a DTx program for patients with cancer, as measured by engagement, retention, and acceptability. In addition, we explored the effects of the program on cancer-related QoL. Methods: We conducted a 4-week single-arm trial in Iceland, where DTx was delivered through a smartphone app. The intervention consisted of patient education about mindfulness, sleep, stress, and nutrition; lifestyle coaching; and the completion of daily missions for tracking physical activity and exercise, reporting patient-reported outcomes (PROs), practicing mindfulness, and logging healthy food intake. Information on program engagement and retention, step goal attainment, as well as PROs were collected throughout the study. QoL was measured using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30 at baseline and follow-up. Results: In total, 30 patients with cancer undergoing active therapy were enrolled, and 29 registered in the app (23 female, 18 with breast cancer; mean age 52.6, SD 11.5 years). Overall, 97{\%} (28/29) of participants were active in 3 of the 4 weeks and completed the pre- and postprogram questionnaires. The weekly active days (median) were 6.8 (IQR 5.8-6.8), and 72{\%} (21/29) of participants were active at least 5 days a week. Users interacted with the app on average 7.7 (SD 1.9) times per day. On week 1, all 29 participants used the step counter and logged an average of 20,306 steps; 21 (72{\%}) participants reached their step goals of at least 3000 steps per day. On week 4, of the 28 active users, 27 (96{\%}) were still logging their steps, with 19 (68{\%}) reaching their step goals. Of the 28 participants who completed the satisfaction questionnaire, 25 (89{\%}) were likely to recommend the program, 23 (82{\%}) said the program helped them deal with the disease, and 24 (86{\%}) said it helped them remember their medication. QoL assessment showed that the average global health status, functioning, and symptom burden remained stable from baseline to follow-up. In all, 50{\%} (14/28) of participants reported less pain, and the average pain score decreased from 31 (SD 20.1) to 22.6 (SD 23.2; P=.16). There was no significant change in PROs on the quality of sleep, energy, and stress levels from the first to the last week. Conclusions: The high retention, engagement, and acceptability found in this study demonstrate that multidisciplinary DTx is feasible for patients with cancer. A longer, full-scale randomized controlled trial is currently being planned to evaluate the efficacy of the intervention. ", issn="2561-326X", doi="10.2196/39764", url="https://formative.www.mybigtv.com/2022/10/e39764", url="https://doi.org/10.2196/39764", url="http://www.ncbi.nlm.nih.gov/pubmed/36227639" }