TY - JOUR AU - Gudmundsson, G Haukur AU - Mészáros, Judit AU - Björnsdóttir， Ágústa E AU - Ámundadóttir, María L AU - Thorvardardottir, Gudrun E AU - Magnusdottir, Erna AU - Helgadottir, Halla AU - Oddsson, Saemundur PY - 2022 DA - 2022/10/13 TI -评估癌症患者积极治疗期间数字治疗方案的可行性:干预前后研究JO - JMIR Form Res VL - 6is - 10kw -癌症KW -生活方式KW -生活质量KW -移动应用程序KW -数字治疗KW -自我管理KW -体育活动KW -手机AB -背景:越来越多的证据表明，生活方式干预可以改善癌症患者的症状、生活质量(QoL)，甚至总体生存期。数字疗法(DTx)可以帮助实施行为改变，并通过教育、生活方式支持和远程症状监测来增强患者的能力。目的:我们旨在测试DTx计划对癌症患者的可行性，通过参与、保留和可接受性来衡量。此外，我们还探讨了该计划对癌症相关生活质量的影响。方法:我们在冰岛进行了为期4周的单臂试验，通过智能手机应用程序提供DTx。干预包括对患者进行正念、睡眠、压力和营养方面的教育;生活方式指导;完成日常任务，跟踪身体活动和锻炼，报告患者报告的结果(PROs)，练习正念，记录健康食物摄入量。在整个研究过程中收集了关于项目参与和保留、步骤目标实现以及PROs的信息。基线和随访时使用欧洲癌症研究与治疗组织生活质量问卷C30测量生活质量。 Results: In total, 30 patients with cancer undergoing active therapy were enrolled, and 29 registered in the app (23 female, 18 with breast cancer; mean age 52.6, SD 11.5 years). Overall, 97% (28/29) of participants were active in 3 of the 4 weeks and completed the pre- and postprogram questionnaires. The weekly active days (median) were 6.8 (IQR 5.8-6.8), and 72% (21/29) of participants were active at least 5 days a week. Users interacted with the app on average 7.7 (SD 1.9) times per day. On week 1, all 29 participants used the step counter and logged an average of 20,306 steps; 21 (72%) participants reached their step goals of at least 3000 steps per day. On week 4, of the 28 active users, 27 (96%) were still logging their steps, with 19 (68%) reaching their step goals. Of the 28 participants who completed the satisfaction questionnaire, 25 (89%) were likely to recommend the program, 23 (82%) said the program helped them deal with the disease, and 24 (86%) said it helped them remember their medication. QoL assessment showed that the average global health status, functioning, and symptom burden remained stable from baseline to follow-up. In all, 50% (14/28) of participants reported less pain, and the average pain score decreased from 31 (SD 20.1) to 22.6 (SD 23.2; P=.16). There was no significant change in PROs on the quality of sleep, energy, and stress levels from the first to the last week. Conclusions: The high retention, engagement, and acceptability found in this study demonstrate that multidisciplinary DTx is feasible for patients with cancer. A longer, full-scale randomized controlled trial is currently being planned to evaluate the efficacy of the intervention. SN - 2561-326X UR - https://formative.www.mybigtv.com/2022/10/e39764 UR - https://doi.org/10.2196/39764 UR - http://www.ncbi.nlm.nih.gov/pubmed/36227639 DO - 10.2196/39764 ID - info:doi/10.2196/39764 ER -