@文章{信息:doi/10.2196/14973，作者=“Moore, Courtney M和Wiehe, Sarah E和Lynch, Dustin O和Claxton, Gina EM和Landman, Matthew P和Carroll, Aaron E和Musey, Paul I”，标题=“耐甲氧西林金黄色葡萄球菌根除和儿童非殖化研究(第二部分):以患者和家长为中心的非殖化结果”，期刊=“J Participat Med”，年=“2020”，月=“5”，日=“20”，卷=“12”，数=“2”，页=“e14973”，关键词=“以患者为中心的结果;金黄色葡萄球菌;脓肿;非殖民地化;背景:由社区获得性耐甲氧西林金黄色葡萄球菌(MRSA)引起的皮肤和软组织感染(SSTIs)可能导致一些重要的已知医疗结果，包括住院治疗，外科手术，如切口和引流(I{\&}D)，以及需要去殖民化程序以清除皮肤和鼻子中的细菌并防止复发感染。关于MRSA感染的成功治疗与以患者和护理人员为中心的结果相关的研究很少。目的:本研究旨在揭示对患者及其父母重要的MRSA去殖民化结果，以便创建一套用于儿童MRSA根除和去殖民化(MEDiC)研究的原型措施。方法:以人为本的设计(HCD)研讨会进行了4小时，5名青少年(10-18岁)接受了I{\&}D手术，11名儿童的父母接受了I{\&}D手术。研讨会探讨了皮肤感染的患者和家庭经验，以揭示MRSA治疗以患者为中心的结果。研究团队分析了研讨会期间产生的音频和人工制品，并对主题相似性进行编码。 The final themes represent patient-centered outcome domains to be measured in the MEDiC comparative effectiveness trial. Results: The workshop identified 9 outcomes of importance to patients and their parents: fewer MRSA outbreaks, improved emotional health, improved self-perception, decreased social stigma, increased amount of free time, increased control over free time, fewer days of school or work missed, decreased physical pain and discomfort, and decreased financial burden. Conclusions: This study represents an innovative HCD approach to engaging patients and families with lived experience with MRSA SSTIs in the study design and trial development to determine meaningful patient-centered outcomes. We were able to identify 9 major recurrent themes. These themes were used to develop the primary and secondary outcome measures for MEDiC, a prospectively enrolling comparative effectiveness trial. Trial Registration: ClinicalTrials.gov NCT02127658; https://clinicaltrials.gov/ct2/show/NCT02127658 ", issn="2152-7202", doi="10.2196/14973", url="http://jopm.www.mybigtv.com/2020/2/e14973/", url="https://doi.org/10.2196/14973" }