@文章{信息:doi/10.2196/29211，作者=“O'Sullivan, Shaunagh和Schmaal, Lianne和D'Alfonso, Simon和Toenders, Yara Jo和Valentine, Lee和McEnery, Carla和Bendall, Sarah和Nelson, Barnaby和Gleeson, John F和Alvarez-Jimenez, Mario”，标题=“多成分数字干预预测首发精神病治疗结果的特征化使用:聚类分析"，期刊="JMIR Ment Health"，年份="2022"，月份="Apr"，日="7"，卷="9"，数="4"，页数="e29211"，关键词="数字干预";数字健康;青年心理健康;精神疾病;聚类;使用量度;日志数据;背景:多成分数字干预为量身定制和灵活的干预提供了潜力，旨在解决高流失率和增加参与度，这是数字心理健康中关注的一个领域。然而，使用灵活性的增加使得很难确定哪些成分可以改善治疗结果。 Objective: This study aims to identify user profiles on Horyzons, an 18-month digital relapse prevention intervention for first-episode psychosis that incorporates therapeutic content and social networking, along with clinical, vocational, and peer support, and to examine the predictive value of these user profiles for treatment outcomes. A secondary objective is to compare each user profile with young people receiving treatment as usual (TAU). Methods: Participants comprised 82 young people (aged 16-27 years) with access to Horyzons and 84 receiving TAU, recovering from first-episode psychosis. In addition, 6-month use data from the therapy and social networking components of Horyzons were used as features for K-means clustering for joint trajectories to identify user profiles. Social functioning, psychotic symptoms, depression, and anxiety were assessed at baseline and 6-month follow-up. General linear mixed models were used to examine the predictive value of user profiles for treatment outcomes and between each user profile with TAU. Results: A total of 3 user profiles were identified based on the following system use metrics: low use, maintained use of social components, and maintained use of both therapy and social components. The maintained therapy and social group showed improvements in social functioning (F2,51=3.58; P=.04), negative symptoms (F2,51=4.45; P=.02), and overall psychiatric symptom severity (F2,50=3.23; P=.048) compared with the other user profiles. This group also showed improvements in social functioning (F1,62=4.68; P=.03), negative symptoms (F1,62=14.61; P<.001), and overall psychiatric symptom severity (F1,63=5.66; P=.02) compared with the TAU group. Conversely, the maintained social group showed increases in anxiety compared with the TAU group (F1,57=7.65; P=.008). No differences were found between the low use group and the TAU group on treatment outcomes. Conclusions: Continued engagement with both therapy and social components might be key in achieving long-term recovery. Maintained social use and low use outcomes were broadly comparable with TAU, emphasizing the importance of maintaining engagement for improved treatment outcomes. Although the social network may be a key ingredient to increase sustained engagement, as users engaged with this more consistently, it should be leveraged as a tool to engage young people with therapeutic content to bring about social and clinical benefits. ", issn="2368-7959", doi="10.2196/29211", url="https://mental.www.mybigtv.com/2022/4/e29211", url="https://doi.org/10.2196/29211", url="http://www.ncbi.nlm.nih.gov/pubmed/35389351" }