@文章{信息:doi/10.2196/40420，作者=“冯玉恒和赵玉曦，毛玉曦和顾林琪和袁敏敏，洪和陆，军和张，祁和赵，钱和李小红”，标题=“社区中基于家庭的2型糖尿病(T2DM)患者微信干预项目的有效性:随机对照试验”，期刊=“JMIR Mhealth Uhealth”，年=“2023”，月=“3”，日=“20”，卷=“11”，页=“e40420”，关键词=“公共卫生;2型糖尿病;干预;随机对照试验;背景:基于家庭支持和风险认知的干预可以增强2型糖尿病(T2DM)患者的自我保健活动。此外，eHealth教育被认为可以提高家庭成员对T2DM患者的支持。然而，从严格设计的研究中很少有证据表明结合这些方法的干预措施的有效性。目的:本随机对照试验(RCT)旨在评估eHealth家庭健康教育干预对T2DM患者血糖控制、风险认知和自我保健行为改善的有效性。方法:该单中心、双平行组随机对照试验于2019 - 2020年进行。从上海市嘉定区招募患者228例，随机分为干预组和对照组。 The intervention group received an eHealth family intervention based on community management via WeChat, whereas the control group received usual care. The primary outcome was the glycated hemoglobin (HbA1c) level of the patients with T2DM, and the secondary outcomes were self-management behavior (general and specific diet, exercise, blood sugar testing, foot care, and smoking), risk perception (risk knowledge, personal control, worry, optimism bias, and personal risk), and family support (supportive and nonsupportive behaviors). A 2-tailed paired-sample t test was used to compare the participants at baseline and follow-up within the control and intervention groups. An analysis of covariance was used to measure the intervention effect. Results: In total, 225 patients with T2DM were followed up for 1 year. After intervention, they had significantly lower HbA1c values ($\beta$=--.69, 95{\%} CI --0.99 to --0.39; P<.001). They also had improved general diet ($\beta$=.60, 95{\%} CI 0.20 to 1.00; P=.003), special diet ($\beta$=.71, 95{\%} CI 0.34 to 1.09; P<.001), blood sugar testing ($\beta$=.50, 95{\%} CI 0.02 to 0.98; P=.04), foot care ($\beta$=1.82, 95{\%} CI 1.23 to 2.42; P<.001), risk knowledge ($\beta$=.89, 95{\%} CI 0.55 to 1.24; P<.001), personal control ($\beta$=.22, 95{\%} CI 0.12 to 0.32; P<.001), worry ($\beta$=.24, 95{\%} CI 0.10 to 0.39; P=.001), optimism bias ($\beta$=.26, 95{\%} CI 0.09 to 0.43; P=.003), and supportive behaviors ($\beta$=5.52, 95{\%} CI 4.03 to 7.01; P<.001). Conclusions: The eHealth family-based intervention improved glucose control and self-care activities among patients with T2DM by aiding the implementation of interventions to improve T2DM risk perceptions among family members. The intervention is generalizable for patients with T2DM using health management systems in community health centers. Trial Registration: Chinese Clinical Trial Registry ChiCTR1900020736; https://www.chictr.org.cn/showprojen.aspx?proj=31214 ", issn="2291-5222", doi="10.2196/40420", url="https://mhealth.www.mybigtv.com/2023/1/e40420", url="https://doi.org/10.2196/40420", url="http://www.ncbi.nlm.nih.gov/pubmed/36939825" }