一种新型情境即时移动应用程序干预(LowSalt4Life)对成人高血卡塔尔世界杯8强波胆分析压患者钠摄入量的影响先导随机对照试验%A Dorsch,Michael P %A Cornellier,Maria L %A Poggi,Armella D %A Bilgen,Feriha %A Chen,Peiyu %A Wu,Cindy %A An,Lawrence C %A Hummel,Scott L %+密歇根大学药学院，密歇根州安娜堡，48109，美国，1 734 647 1452,mdorsch@med.umich.edu %K高血压%K钠摄入量%K地理隔离%K mHealth %D 2020 %7 10.8.2020 %9原文% jjmir mHealth Uhealth %G英文%X在美国，高钠饮食摄入量是一个重要的公共健康问题。高钠摄入量与高血压和心血管疾病的高风险有关。目的:本研究的目的是评估即时适应性移动应用程序干预，即LowSalt4Life，对减少成人高血压患者钠摄入量的影响。方法:本研究采用单中心、前瞻性、开放标签随机对照试验，将50名年龄≥18岁、正在接受高血压治疗的患者随机(1:1，按性别分层)分为App组(LowSalt4Life干预)和No App组(常规饮食建议)2组，为期8周。主要终点是使用川崎方程估计的24小时尿钠排泄量的变化，使用非配对双侧t检验进行分析。次要结果包括通过食物频率问卷(FFQ)测量的钠摄入量的变化，24小时尿钠排泄量，血压水平和自我报告的低钠饮食的信心。结果:从基线到第8周，App组与No App组相比，根据尿样计算的kawasaki估计24小时尿钠排泄量显著减少(分别为-462 [SD 1220] mg和381 [SD 1460] mg;P = 03)。 The change in the 24-hour urinary sodium excretion was –637 (SD 1524) mg in the App group and –322 (SD 1485) mg in the No App group (P=.47). The changes in the estimated sodium intake as measured by 24-hour dietary recall and by FFQ in the App group were –1537 (SD 2693) mg and –1553 (SD 1764) mg while those in the No App group were –233 (SD 2150) mg and –515 (SD 1081) mg, respectively (P=.07 and P=.01, respectively). The systolic blood pressure change from baseline to week 8 in the App group was –7.5 mmHg while that in the No App group was –0.7 mmHg (P=.12), but the self-confidence in following a low-sodium diet was not significantly different between the 2 groups. Conclusions: This study shows that a contextual just-in-time mobile app intervention resulted in a greater reduction in the dietary sodium intake in adults with hypertension than that in the control group over a 8-week period, as measured by the estimated 24-hour urinary sodium excretion from spot urine and FFQ. The intervention group did not show a significant difference from the control group in the self-confidence in following a low sodium diet and in the 24-hour urinary sodium excretion or dietary intake of sodium as measured by the 24-hour dietary recall. A larger clinical trial is warranted to further elucidate the effects of the LowSalt4Life intervention on sodium intake and blood pressure levels in adults with hypertension. Trial Registration: ClinicalTrials.gov NCT03099343; https://clinicaltrials.gov/ct2/show/NCT03099343 International Registered Report Identifier (IRRID): RR2-10.2196/11282 %M 32663139 %R 10.2196/16696 %U http://mhealth.www.mybigtv.com/2020/8/e16696/ %U https://doi.org/10.2196/16696 %U http://www.ncbi.nlm.nih.gov/pubmed/32663139