@文章{信息:doi/10.2196/35785，作者=“任宁军、李宁军、万元生、王正伟、若兰、张文新、Dzakah、Emmanuel Enoch、张俊辉、李俊辉、爱玲、范伟宋”，标题=《1990 - 2019年中国老年人艾滋病死亡规律:年龄-期-队列分析》，期刊=《JMIR公共卫生监测》，年=“2022”，月=“11”，日=“17”，卷=“8”，数=“11”，页数=“e35785”，关键词=“HIV;艾滋病;老化;死亡率;趋势;age-period-cohort模型;背景:随着抗逆转录病毒治疗效果的提高和人口结构的变化，中国老年艾滋病患者的问题日益严峻，忽视他们的感染可能会造成更严重的社会问题，加剧控制艾滋病传播的难度，增加死亡风险。目的:研究1990 - 2019年中国不同年龄、不同时期、不同队列人群死亡率的变化趋势，揭示年龄、不同时期、不同队列与艾滋病病毒负担之间的关系，为预防弱势目标人群艾滋病病毒相关死亡的资源配置提供指导。方法:我们从全球疾病负担中提取了艾滋病毒或艾滋病死亡率数据。联合点回归模型用于检测HIV或艾滋病趋势的变化。 The age-period-cohort model was used to explore the age, period, and cohort effects. Results: The trends in age-standardized mortality rates in HIV or AIDS were increased in both genders, from 0.50 to 4.54/105 individuals for males, and from 0.19 to 1.43/105 individuals for females. Joinpoint regression model showed the average annual percentage change of age-standardized mortality rates was 7.0 for male and 6.4 for female individuals, showing an increasing trend. The age effect of male HIV or AIDS mortality showed a net increase of 0.59 (--0.21 to 0.38) from the ages 50-79 years. There is a gradual upward trend in the change in risk of death from HIV or AIDS for the period effect among the older population, lowest at ages 50-54 years (--0.80 for male and --0.78 for female individuals) and highest at ages 75-79 years (0.86 for male and 0.69 for female individuals). The variation of cohort effects was complex, but both genders had a nearly consistent tendency; people born in 1920-1929 had the lowest cohort effect, and those born in 1950-1954 had the highest values. Conclusions: Our study showed a marked rise in HIV mortality for both genders in China from 1990 to 2019. Aging is an important issue in current HIV prevention and control. There is an urgent need to promote HIV testing and health education. Our findings will help predict future HIV or AIDS mortality changes and identify age-specific priority populations for intervention. ", issn="2369-2960", doi="10.2196/35785", url="https://publichealth.www.mybigtv.com/2022/11/e35785", url="https://doi.org/10.2196/35785", url="http://www.ncbi.nlm.nih.gov/pubmed/36394944" }