@Article{信息:doi 10.2196 / / jmir。9052，作者="Vilchis-Gil, Jenny and Kl{\"u}nder-Kl{\"u}nder, Miguel and Flores-Huerta, Samuel"，标题="在使用电子媒体和面对面会议改变生活方式的综合干预后对学龄儿童代谢生物标志物的影响:社区试验"，期刊="J Med Internet Res"，年="2018"，月="2"，日="05"，卷="20"，数="2"，页="e44"，关键词="肥胖;孩子;早期干预(教育);胰岛素抵抗;背景:肥胖是一种伴有代谢改变的慢性低强度炎症状态，如果在儿童时期获得，成年后会导致严重疾病。鼓励健康的饮食习惯和体育活动是预防和治疗肥胖及其并发症的基础。目的:评估促进学校健康饮食习惯和体育活动的综合干预措施如何影响儿童的代谢生物标志物。方法:在这项研究中，在墨西哥城的四所小学中，两组在他们学校招募的儿童被分配到12个月的干预组(IG)，另外两组被分配到对照组(CGs)。干预措施有两个组成部分:(1)家长/学童亲自参加宣传健康饮食和体育活动习惯的教育课程，并提供了书面资料; and (2) parents were able to seek information through a website, and also received brief weekly mobile phone text messages. Anthropometric measurements and fasting blood samples were taken from both groups of children at baseline and again after 12 months. Results: The study involved 187 children in the IG and 128 in the CG. Regardless of each child's nutritional status at the beginning of the study, the intervention improved metabolic parameters; the IG showed a negative effect on glucose concentrations (--1.83; CI 95{\%} --3.06 to -0.60), low-density lipoprotein-cholesterol (--2.59; CI 95{\%} --5.12 to --0.06), insulin (--0.84; CI 95{\%} --1.31 to --0.37), and homeostasis model to assess the insulin resistance index (HOMA-IR; --0.21; CI 95{\%} --0.32 to --0.09) in comparison to the CG. HOMA-IR improved in children who had higher than baseline body mass index z-scores. Conclusions: Intervention through multiple components that promoted healthier eating and physical activity habits improved the metabolic parameters of the children in the study after one year, regardless of their nutritional status. ", issn="1438-8871", doi="10.2196/jmir.9052", url="//www.mybigtv.com/2018/2/e44/", url="https://doi.org/10.2196/jmir.9052", url="http://www.ncbi.nlm.nih.gov/pubmed/29402762" }