@文章{信息:doi/10.2196/13385，作者=“本桥，友光和平野，友信和奥村，Kosuke和Kashiyama，真纪子和市川，大介和上野，太郎”，标题=“安全可扩展的移动健康数据管理使用区块链结合客户端Hashchain:系统设计和验证”，期刊=“J医学互联网Res”，年=“2019”，月=“五月”，日=“16”，卷=“21”，数=“5”，页=“e13385”，关键词=“移动健康;电子健康记录;区块链;端hashchain;背景:区块链作为一种用于安全数据管理的创新技术正在许多领域崭露头角，包括医疗实践。分布式区块链网络对网络故障具有容忍度，注册数据抗篡改和修改。该技术与移动医疗(mHealth)等数字医学有很高的亲和力，并为医疗数据提供可靠性，无需第三方的劳动密集型贡献。另一方面，在注册到区块链网络之前，医疗数据的可靠性没有得到保障。此外，还存在关于如何在区块链网络中处理和验证客户端移动设备以避免模仿的问题。目的:本研究的目的是设计和验证一个移动健康系统，使医疗数据的兼容性、安全性和可扩展性使用区块链技术。 Methods: We designed an mHealth system that sends medical data to the blockchain network via relay servers. The architecture provides scalability and convenience of operation of the system. In order to ensure the reliability of the data from clients' mobile devices, hash values with chain structure (client hashchain) were calculated in the clients' devices and the results were registered on the blockchain network. Results: The system was applied and deployed in mHealth for insomnia treatment. Clinical trials for mHealth were conducted with insomnia patients. Medical data of the recruited patients were successfully registered with the blockchain network via relay servers along with the hashchain calculated on the clients' mobile devices. The correctness of the data was validated by identifying illegal data, which were made by simulating fraudulent access. Conclusions: Our proposed mHealth system, blockchain combined with client hashchain, ensures compatibility of security and scalability in the data management of mHealth medical practice. Trial Registration: UMIN Clinical Trials Registry UMIN000032951; https://upload.umin.ac.jp/cgi-open- bin/ctr{\_}e/ctr{\_}view.cgi?recptno=R000037564 (Archived by WebCite at http://www.webcitation.org/78HP5iFIw) ", issn="1438-8871", doi="10.2196/13385", url="//www.mybigtv.com/2019/5/e13385/", url="https://doi.org/10.2196/13385", url="http://www.ncbi.nlm.nih.gov/pubmed/31099337" }

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