@文章{信息:doi/10.2196/15863,作者="Linde, Ditte S和Andersen, Marianne S和Mwaiselage, Julius和Manongi, Rachel和Kjaer, Susanne K和Rasch, Vibeke",标题="单向短信对人乳头瘤病毒阳性坦桑尼亚妇女参加后续宫颈癌筛查的有效性(Connected2Care):平行组随机对照试验”,期刊=“J Med Internet Res”,年=“2020”,月=“4”,日=“2”,卷=“22”,数=“4”,页数=“e15863”,关键词=“远程医疗”;子宫颈癌;人乳头状瘤病毒;癌症的早期发现;背景:在资源有限的国家,快速人乳头瘤病毒(HPV) DNA检测是一种新兴的宫颈癌筛查策略,但它需要对HPV检测呈阳性的妇女进行随访。目的:本研究旨在确定单程短信是否能提高hpv阳性女性14个月随访宫颈癌筛查的出勤率。方法:这项多中心、平行组随机对照试验在坦桑尼亚的3家医院进行。符合条件的参与者年龄在25岁至60岁之间,在患者发起的快速HPV检测中检测呈阳性,已被告知其HPV结果,并拥有有效号码的私人手机。通过短信系统中的一种合并算法,参与者以1:1的比例随机分配到干预组或对照组。 The intervention group received one-way text messages, and the control group received no text messages. The primary outcome was attendance at a 14-month health provider-initiated follow-up screening. Participants were not blinded, but outcome assessors were. The analysis was based on intention to treat. Results: Between August 2015 and July 2017, 4080 women were screened for cervical cancer, of which 705 were included in this trial---358 women were allocated to the intervention group, and 347 women were allocated to the control group. Moreover, 16 women were excluded before the analysis because they developed cervical cancer or died (8 from each group). In the intervention group, 24.0{\%} (84/350) women attended their follow-up screening, and in the control group, 23.8{\%} (80/335) women attended their follow-up screening (risk ratio 1.02, 95{\%} CI 0.79-1.33). Conclusions: Attendance to a health provider-initiated follow-up cervical cancer screening among HPV-positive women was strikingly low, and one-way text messages did not improve the attendance rate. Implementation of rapid HPV testing as a primary screening method at the clinic level entails the challenge of ensuring a proper follow-up of women. Trial Registration: ClinicalTrials.gov NCT02509702; https://clinicaltrials.gov/ct2/show/NCT02509702. International Registered Report Identifier (IRRID): RR2-10.2196/10.2196/15863 ", issn="1438-8871", doi="10.2196/15863", url="//www.mybigtv.com/2020/4/e15863/", url="https://doi.org/10.2196/15863", url="http://www.ncbi.nlm.nih.gov/pubmed/32238335" }
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