期刊文章JMIR出版物解决酒精使用问题的数字干预(“黎明”计划):卡塔尔世界杯8强波胆分析准实验随机对照试验%A Tait,Robert J %A Paz Castro,Raquel %A Kirkman,Jessica Jane Louise %A Moore,Jamie Christopher %A Schaub,Michael P %+科廷大学健康科学学院国家药物研究所，GPO Box U 1981，珀斯，6845，澳大利亚，61 892661610，robert.tait@curtin.edu.au酒精消费互联网数字健康干预研究社会营销健康促进背景:酒精使用在许多社会中普遍存在，并对健康产生重大不利影响，但有效干预措施的可用性限制了那些希望帮助改变其酒精使用模式的人的治疗选择。目的:本研究评估了新的Daybreak程序，该程序可通过移动应用程序和桌面访问，由Hello Sunday Morning开发，旨在支持希望改变与酒精关系的高危饮酒人群。特别是，我们比较了通过实时聊天信息添加在线指导(干预组)和其他自我指导计划(对照组)的效果。方法:我们将干预设计为随机对照试验，但作为一些人(n=48;11.9%)能够使用在线辅导，主要分析包括所有参与者。我们在一个月和三个月的随访中收集了在线调查。主要结果是酒精风险的变化(用酒精使用障碍识别测试-消费[AUDIT-C]评分测量)，但其他结果包括每周标准饮酒量、酒精相关的失效天数、心理困扰(Kessler-10)和生活质量(EUROHIS-QOL)。参与该项目的标志包括在网站上的帖子和对他人帖子的评论。 The primary analysis used Weighted Generalized Estimating Equations. Results: We recruited 398 people to the intervention group (50.2%) and 395 people to the control group (49.8%). Most were female (71%) and the mean age was 40.1 years. Most participants were classified as probably dependent (550, 69%) on the AUDIT–10, with 243 (31%) classified with hazardous or harmful consumption. We followed up with 334 (42.1%) participants at one month and 293 (36.9%) at three months. By three months there were significant improvements in AUDIT–C scores (down from mean 9.1 [SD 1.9] to 5.8 [SD 3.1]), alcohol consumed per week (down from mean 37.1 [SD 28.3] to mean 17.5 [SD 18.9]), days out of role (down from mean 1.6 [SD 3.6] to 0.5 [SD 1.6]), quality of life (up from 3.2 [SD 0.7] to 3.6 [SD 0.7]) and reduced distress (down from 24.8 [SD 7.0] to 19.0 [SD 6.6]). Accessing online coaching was not associated with improved outcomes, but engagement with the program (eg, posts and comments on the posts of others) were significantly associated with improvements (eg, in AUDIT–C, alcohol use and EUROHIS-QOL). Reduced alcohol use was found for both probably dependent (estimated marginal mean of 40.8 to 20.1 drinks) and hazardous or harmful alcohol users (estimated marginal mean of 22.9 to 11.9 drinks). Conclusions: Clinically significant reductions in alcohol use were found, as well as reduced alcohol risk (AUDIT–C) and days out of role. Importantly, improved alcohol-related outcomes were found for both hazardous or harmful and probably dependent drinkers. Since October 2016, Daybreak has reached more than 50,000 participants. Therefore, there is the potential for the program to have an impact on alcohol-related problems at a population health level, importantly including an effect on probably dependent drinkers. Trial Registration: Australian New Zealand Clinical Trials Registry: ACTRN12618000010291; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=373110 International Registered Report Identifier (IRRID): RR2-10.2196/9982 %M 31486406 %R 10.2196/14967 %U //www.mybigtv.com/2019/9/e14967/ %U https://doi.org/10.2196/14967 %U http://www.ncbi.nlm.nih.gov/pubmed/31486406