在幼儿中推广季节性流感疫苗的社交网络干预的有效性和父母的可接受性:卡塔尔世界杯8强波胆分析随机对照试验%廖a，邱艳%A Fielding,Richard %A Cheung,Yee Tak Derek %A Lian,Jinxiao %A Yuan,Jiehu %A Lam,Wendy Wing Tak %+香港大学，中国香港薄扶林沙宣道7号(香港)，852 3917 9289,qyliao11@hku.hk %K流感疫苗接种%K社交媒体%K干预%K儿童%D 2020 %7 28.2.2020 %9 Original Paper %J J Med Internet Res %G English %X背景:全球幼儿季节性流感疫苗(SIV)覆盖率仍然较低。WhatsApp Messenger等移动社交网络应用程序是很有前途的健康干预工具。目的:这是一项初步研究，旨在测试社交网络干预的有效性和父母的接受程度，该干预措施每周发送疫苗接种提醒，并鼓励母亲通过WhatsApp讨论组交流与SIV相关的观点和经验，以促进儿童SIV。第二个目标是检查引入时间压力对母亲对儿童SIV疫苗接种决策的影响。这是通过推荐接种时间的倒计时来完成的。方法:将6 ~ 72月龄儿童的母亲随机分为对照组或两个社交网络干预组，通过WhatsApp讨论组以5:2:2的比例接收带有(SNI+TP)或不带有(SNI - TP)时间压力成分的疫苗接种提醒。所有参与者首先完成了基线评估。SNI - TP组和SNI+TP组随后在2017年10月至12月期间每周收到疫苗接种提醒，并参加了由卫生专业人员主持的关于SIV的WhatsApp讨论。所有参与者在2018年4月至5月期间完成了随访评估。 Results: A total of 84.9% (174/205), 71% (57/80), and 75% (60/80) who were allocated to the control, SNI–TP, and SNI+TP groups, respectively, completed the outcome assessment. The social networking intervention significantly promoted mothers’ self-efficacy for taking children for SIV (SNI–TP: odds ratio [OR] 2.69 [1.07-6.79]; SNI+TP: OR 2.50 [1.13-5.55]), but did not result in significantly improved children’s SIV uptake. Moreover, after adjusting for mothers’ working status, introducing additional time pressure reduced the overall SIV uptake in children of working mothers (OR 0.27 [0.10-0.77]) but significantly increased the SIV uptake among children of mothers without a full-time job (OR 6.53 [1.87-22.82]). Most participants’ WhatsApp posts were about sharing experience or views (226/434, 52.1%) of which 44.7% (101/226) were categorized as negative, such as their concerns over vaccine safety, side effects and effectiveness. Although participants shared predominantly negative experience or views about SIV at the beginning of the discussion, the moderator was able to encourage the discussion of more positive experience or views and more knowledge and information. Most intervention group participants indicated willingness to receive the same interventions (110/117, 94.0%) and recommend the interventions to other mothers (102/117, 87.2%) in future Conclusions: Online information support can effectively promote mothers’ self-efficacy for taking children for SIV but alone it may not sufficient to address maternal concerns over SIV to achieve a positive vaccination decision. However, the active involvement of health professionals in online discussions can shape positive discussions about vaccination. Time pressure on decision making interacts with maternal work status, facilitating vaccination uptake among mothers who may have more free time, but having the opposite effect among busier working mothers. Trial Registration: Hong Kong University Clinical Trials Registry HKUCTR-2250; https://tinyurl.com/vejv276 %M 32130136 %R 10.2196/16427 %U //www.mybigtv.com/2020/2/e16427/ %U https://doi.org/10.2196/16427 %U http://www.ncbi.nlm.nih.gov/pubmed/32130136