杂志文章@ 1438-8871 %I JMIR出版物V 24% N 8卡塔尔世界杯8强波胆分析% P 373868 %T用于接受癌症化疗的患者的无创中性粒细胞减少筛查设备(PointCheck)的可用性评估:混合方法观察研究% Lamaj Ganimete % Pablo-Trinidad,阿尔贝托%巴特沃斯,伊恩%一个铃铛,诺兰% Benasutti,瑞安% Bourquard, Aurelien % Sanchez-Ferro,阿尔瓦罗·% Castro-Gonzalez,卡洛斯% Jimenez-Ubieto,安娜%鲍曼,第谷% Rodriguez-Izquierdo,安东尼娅% Pottier,伊丽莎白%谢尔顿,安东尼% Martinez-Lopez,华金%斯隆,约翰。马克% +白色实验室,公司,8圣玛丽街,没有613年,波士顿,MA, 02215年,美国,1 781 954 0250,ganimete@leuko.com %K数字健康%K可用性%K以患者为中心的护理%K远程监测%K决策支持系统%K白细胞%K诊断%K医疗设备%K癌症%K化疗%K感染%K白细胞%K技术%D 2022 %7 9.8.2022 %9原始论文%J J医学互联网Res %G英文%X背景:接受细胞毒性化疗的癌症患者由于治疗而面临严重感染的风险增加，这降低了他们的白细胞计数，更具体地说，降低了他们的绝对中性粒细胞计数。这种情况被称为中性粒细胞减少症。伴有发热的中性粒细胞减少症被称为发热性中性粒细胞减少症，是化疗的一种常见副作用，死亡率高。及时发现严重的中性粒细胞减少症(<500绝对中性粒细胞计数/μL)对于发现和处理发热性中性粒细胞减少症至关重要。目前的方法依赖于抽血，这将它们限制在临床环境中，不允许频繁或便携式监测。在这项研究中，我们在没有临床监督的模拟家庭环境中演示了PointCheck的可用性，PointCheck是一种用于中性粒细胞减少症筛查的非侵入性设备。PointCheck自动通过手指皮肤进行显微检查，对流经浅表微毛细血管的血液进行成像，并实现对中性粒细胞减少状态的远程监测，而不需要静脉穿刺。 Objective: This study aimed to evaluate the usability of PointCheck, a noninvasive optical technology for screening severe neutropenia, with the goal of identifying potential user interface, functionality, and design issues from the perspective of untrained users. Methods: We conducted a multicenter study using quantitative and qualitative approaches to evaluate the usability of PointCheck across 154 untrained participants. We used a mixed method approach to gather usability data through user testing observations, a short-answer qualitative questionnaire, and a standardized quantitative System Usability Scale (SUS) survey to assess perceived usability and satisfaction. Results: Of the 154 participants, we found that 108 (70.1%) scored above 80.8 on the SUS across all sites, with a mean SUS score of 86.1 across all sites. Furthermore, the SUS results indicated that, out of the 151 users who completed the SUS survey, 145 (96%) found that they learned how to use PointCheck very quickly, and 141 (93.4%) felt very confident when using the device. Conclusions: We have shown that PointCheck, a novel technology for noninvasive, home-based neutropenia detection, can be safely and effectively operated by first-time users. In a simulated home environment, these users found it easy to use, with a mean SUS score of 86.1, indicating an excellent perception of usability and placing this device within the top tenth percentile of systems evaluated for usability by the SUS. Trial Registration: ClinicalTrials.gov NCT04448314; https://clinicaltrials.gov/ct2/show/NCT04448314 (Hospital Universitario 12 de Octubre registration) and NCT04448301; https://clinicaltrials.gov/ct2/show/NCT04448301 (Boston Medical Center registration) %M 35943786 %R 10.2196/37368 %U //www.mybigtv.com/2022/8/e37368 %U https://doi.org/10.2196/37368 %U http://www.ncbi.nlm.nih.gov/pubmed/35943786