基于社交网络的男男性行为者艾滋病毒自我检测方法的级联实现卡塔尔世界杯8强波胆分析香港中文大学新发传染病研究中心，香港威尔斯亲王医院研究生教育中心207室，电话:852 22528862;sslee@cuhk.edu.hk %K社区检测服务%K横断面研究%K艾滋病毒自检%K艾滋病毒检测%K实施级联%K男男性行为者%K社会网络%K病毒传播%D 2023 %7 26.4.2023 %9背景:艾滋病毒检测是实现到2030年终结艾滋病流行的快车道目标的战略基石。自我测试已被证明是男男性行为者(MSM)的有效健康干预措施。虽然世界卫生组织建议使用基于社会网络的方法分发艾滋病毒自我检测，但其实施包括多个步骤，需要进行适当评估。目的:本研究旨在评估基于社交网络的艾滋病自我检测方法在香港对从未接受过检测的男同性恋者的实施级联性。方法:这是一个横断面研究。种子MSM参与者是通过不同的网络渠道招募的，他们又邀请他们的同龄人参加这项研究。设立了一个网络平台，以支持招聘和转介程序。在完成一份自我管理的问卷后，参与者可以要求进行口服液或手指刺破艾滋病毒自检，有或没有实时支持。 Referrals could be made upon uploading the test result and passing the web-based training. Characteristics of participants completing each of these steps and their preferences for the type of HIV self-test were evaluated. Results: A total of 463 MSM were recruited, including 150 seeds. Participants recruited by seeds were less likely to have previously been tested for HIV (odds ratio [OR] 1.80, 95% CI 1.06-3.04, P=.03) and have lower confidence in performing self-tests (OR 0.66, 95% CI 0.45-0.99, P=.045). Almost all (434/442, 98%) MSM who completed the questionnaire requested a self-test, of whom 82% (354/434) had uploaded their test results. Participants requesting support were new to self-testing (OR 3.65, 95% CI 2.10-6.35, P<.001) and less confident in carrying out the self-test correctly (OR 0.35, 95% CI 0.22-0.56, P<.001). More than half (216/354, 61%) of the eligible participants initiated the referral process by attempting the web-based training with a passing rate of 93% (200/216). They were more likely to have sought sex partners (OR 2.20, 95% CI 1.14-4.25, P=.02), especially through location-based networking apps (OR 2.13, 95% CI 1.31-3.49, P=.002). They also gave higher usability scores along the implementation cascade (median 81 vs 75, P=.003). Conclusions: The social network approach was effective in diffusing HIV self-tests in the MSM community and reaching nontesters. Support and option to choose a preferable type of self-test are essential to address users’ individual needs when delivering HIV self-tests. A positive user experience throughout the processes along the implementation cascade is vital to transform a tester into a promoter. Trial Registration: ClinicalTrials.gov NCT04379206; https://clinicaltrials.gov/ct2/show/NCT04379206 %M 37099364 %R 10.2196/46514 %U //www.mybigtv.com/2023/1/e46514 %U https://doi.org/10.2196/46514 %U http://www.ncbi.nlm.nih.gov/pubmed/37099364