TY -非盟的西尔维娅,路易莎G盟,卢恩,Mitchell R AU - Obedin-Maliver,朱诺盟,麦克伯尼,罗伯特·N AU -阿普W本杰明AU - Nosheny,雷切尔•L AU - Mularski理查德AU -长,米莉维盟——默克尔,彼得•AU -普莱彻马克J AU - Tovey,罗伯塔E盟——Scalchunes克里斯托弗AU -萨特芬,丽贝卡AU -马丁,安年代AU -角,伊丽莎白J盟——奥博伊,梅根盟球,丽莎盟——Seid迈克尔AU -取消,苏珊盟——Greenebaum苏菲AU -乔治,Nevita盟——法国,Noah J AU - Faria, Caylin M AU - Puvanich, Nicha AU - Rabideau, Dustin J AU - Selvaggi, Caitlin A AU - Yu, Chu AU - Faraone, Stephen V AU - Venkatachalam, Shilpa AU - McCall, Debbe AU - Terry, Sharon F AU - Deckersbach, Thilo AU - Nierenberg, Andrew A PY - 2022 DA - 2022/9/12 TI -基于网络的正念幸福感干预:随机比较效果试验JO - J Med Internet Res SP - e35620 VL - 24 IS - 9 KW -正念KW -幸福感KW -网络KW -对照试验KW -临床试验KW -认知治疗KW -干预KW -心理健康KW -正念KW -电子健康KW -手机AB -背景:正念可以通过训练个体专注于当下而不判断他们的想法来提高整体幸福感。然而，目前尚不清楚需要多少正念练习和训练来提高幸福感。目的:本研究的主要目的是确定一个标准的8期基于网络的正念认知治疗(MBCT)项目，与一个简短的3期正念干预相比，是否能改善参与者的整体幸福感。此外，我们试图探讨治疗效果是否根据参与者的基线特征(即调节因子)而不同。方法:参与者从17个患者驱动的研究网络中招募，这些网络社区由对共同研究领域感兴趣的利益相关者组成。参与者被随机分为两组，一组接受标准的8期MBCT，另一组接受在线的3期正念训练干预。参与者被跟踪了12周。这项研究的主要结果是幸福感，用世界卫生组织的五项幸福感指数来衡量。 We hypothesized that MBCT would be superior to a brief mindfulness training. Results: We randomized 4411 participants, 3873 (87.80%) of whom were White and 3547 (80.41%) of female sex assigned at birth. The mean baseline World Health Organization—Five Well-Being Index score was 50.3 (SD 20.7). The average self-reported well-being in each group increased over the intervention period (baseline to 8 weeks; model-based slope for the MBCT group: 0.78, 95% CI 0.63-0.93, and brief mindfulness group: 0.76, 95% CI 0.60-0.91) as well as the full study period (ie, intervention plus follow-up; baseline to 20 weeks; model-based slope for MBCT group: 0.41, 95% CI 0.34-0.48; and brief mindfulness group: 0.33, 95% CI 0.26-0.40). Changes in self-reported well-being were not significantly different between MBCT and brief mindfulness during the intervention period (model-based difference in slopes: −0.02, 95% CI −0.24 to 0.19; P=.80) or during the intervention period plus 12-week follow-up (−0.08, 95% CI −0.18 to 0.02; P=.10). During the intervention period, younger participants (P=.05) and participants who completed a higher percentage of intervention sessions (P=.005) experienced greater improvements in well-being across both interventions, with effects that were stronger for participants in the MBCT condition. Attrition was high (ie, 2142/4411, 48.56%), which is an important limitation of this study. Conclusions: Standard MBCT improved well-being but was not superior to a brief mindfulness intervention. This finding suggests that shorter mindfulness programs could yield important benefits across the general population of individuals with various medical conditions. Younger people and participants who completed more intervention sessions reported greater improvements in well-being, an effect that was more pronounced for participants in the MBCT condition. This finding suggests that standard MBCT may be a better choice for younger people as well as treatment-adherent individuals. Trial Registration: ClinicalTrials.gov NCT03844321; https://clinicaltrials.gov/ct2/show/NCT03844321 SN - 1438-8871 UR - //www.mybigtv.com/2022/9/e35620 UR - https://doi.org/10.2196/35620 UR - http://www.ncbi.nlm.nih.gov/pubmed/36094813 DO - 10.2196/35620 ID - info:doi/10.2196/35620 ER -